To diagnose thyrotoxicosis, tests should show raised thyroid hormone levels in the blood (raised thyroxine and/or triiodothyronine) and low, undetectable thyroid stimulating hormone (a hormone released by the pituitary gland that stimulates the thyroid gland to release its hormones).
How can you tell the difference between hyperthyroidism and thyrotoxicosis?
Hyperthyroidism is characterised by increased thyroid hormone synthesis and secretion from the thyroid gland, whereas thyrotoxicosis refers to the clinical syndrome of excess circulating thyroid hormones, irrespective of the source.
How is thyrotoxicosis treated?
Generally, thyrotoxicosis should be evaluated and treated by an endocrinologist. Therapy, including radioactive iodine and antithyroid medication, requires careful follow-up, which is best performed by a specialist.
How long does thyrotoxicosis last?
The thyrotoxic phase lasts for 1-3 months and is associated with symptoms including anxiety, insomnia, palpitations (fast heart rate), fatigue, weight loss, and irritability. The hypothyroid phase typically occurs 1-3 months after the thyrotoxic phase and may last up to 9 – 12 months.
What is the most common cause of thyrotoxicosis?
The most common cause of thyrotoxicosis is Graves’ disease, followed by toxic multinodular goiter (TMNG) and toxic adenoma (TA). Other causes include thyroiditis, subacute thyroiditis, painless thyroiditis, and gestational hyperthyroidism.
Does thyrotoxicosis go away?
Hyperthyroidism typically does not go away on its own. Most people need treatment to make hyperthyroidism go away. After treatment, many people develop hypothyroidism (too little thyroid hormone).
How does thyrotoxicosis affect the body?
Hyperthyroidism (overactive thyroid) occurs when your thyroid gland produces too much of the hormone thyroxine. Hyperthyroidism can accelerate your body’s metabolism, causing unintentional weight loss and a rapid or irregular heartbeat.
Is thyrotoxicosis an emergency?
The extreme manifestation of thyrotoxicosis is thyroid storm, which manifests as an acute, severe, life‐threatening hypermetabolic state caused either by excessive release of thyroid hormones, causing adrenergic hyperactivity, or altered peripheral response to thyroid hormone following the presence of one or more …
Is thyrotoxicosis an autoimmune disease?
GD is a systemic autoimmune thyroid disorder characterized by the infiltration of immune effector cells and thyroid-antigen-specific T cells into the thyroid and thyroid stimulating hormone receptor (TSHR) expressing tissues, i.e. orbit, skin, with the production of autoantibodies to well-defined thyroidal antigens.
Can thyrotoxicosis cause heart failure?
Key points. Heart failure in thyrotoxicosis is well recognized. Thyrotoxicosis is associated with a high cardiac output state and heart failure in this context is usually associated with underlying cardiac disease. There is a high incidence of atrial dysrhythmia, particularly atrial fibrillation, in thyrotoxicosis.
What triggers thyrotoxicosis?
What causes thyrotoxicosis? The main cause of thyrotoxicosis is hyperthyroidism, which is an overactivity of the thyroid gland resulting in it producing excess levels of thyroid hormones. If the hyperthyroidism is due to an autoimmune cause, it is called Graves’ disease.
How serious is thyrotoxicosis?
Untreated thyrotoxicosis can lead to serious medical complications such as heart rhythm disturbances and osteoporosis caused from the long-term effects of hormone overproduction.
What does a thyroid storm feel like?
Symptoms of thyroid storm include: Feeling extremely irritable or grumpy. High systolic blood pressure, low diastolic blood pressure, and fast heartbeat. Nausea, vomiting, or diarrhea.
Is thyrotoxicosis the same as hypothyroidism?
Hyperthyroidism refers to an overactive thyroid (when it produces too much thyroid hormone) and hypothyroidism refers to an underactive thyroid (when it does not produce enough). These two conditions often have different signs and symptoms.
What is the difference between primary and secondary thyrotoxicosis?
Primary hyperthyroidism is the term used when the pathology is within the thyroid gland. Secondary hyperthyroidism is the term used when the thyroid gland is stimulated by excessive thyroid-stimulating hormone (TSH) in the circulation.
Is thyrotoxicosis and thyroid storm the same thing?
Thyrotoxicosis is a common endocrine condition that may be secondary to a number of underlying processes. Thyroid storm (also known as thyroid or thyrotoxic crisis) represents the severe end of the spectrum of thyrotoxicosis and is characterized by compromised organ function.