Subclinical hypothyroidism or mild thyroid failure is a common problem, with a prevalence of 3% to 8% in the population without known thyroid disease.
Does subclinical hypothyroidism always progress?
According to published research, 3 to 8 percent of people have subclinical hypothyroidism. This condition can progress to full-blown hypothyroidism. In one study, 26.8 percent of those with subclinical hypothyroidism developed full-blown hypothyroidism within 6 years of their initial diagnosis.
What TSH level is considered subclinical hypothyroidism?
Subclinical hypothyroidism is defined as a thyroid stimulating hormone (TSH) level of 4.6 to 10 mIU/L. A normal TSH level is 0.4 to 4.0 and full-blown hypothyroidism is 10 or higher.
What is the prevalence of subclinical hypothyroidism?
In two population-based studies, the prevalence of subclinical hypothyroidism ranged between 7.5–8.5% in women and 4.4% in men [13,14]. Subclinical hypothyroidism prevalence increases in women with increasing age and is more common in elderly females (7–18%) than males (2–15%) [15,16].
Do we treat subclinical hypothyroidism?
Treatment of subclinical hypothyroidism may halt or slow the progression to overt hypothyroidism, but there is no evidence to support this effect. Patients must continue to have TSH monitored at least yearly and be educated to report symptoms or adverse reactions.
Is subclinical hypothyroidism serious?
Subclinical hypothyroidism was not found to increase the risk for stroke in patients over 65 years old , but was associated with a better outcome [82,83]. In contrast, TSH > 10 mIU/L can be linked with an increased risk of heart failure and other cardiovascular events .
How can I reduce my subclinical hypothyroidism?
Initiating levothyroxine replacement therapy is recommended for all patients with a TSH greater than 10 mIU/L, even if the free thyroxine concentration is within normal laboratory range. However, treatment of patients with a serum TSH level between 5 and 10 mIU/L remains controversial.
When do you repeat TSH in subclinical hypothyroidism?
MANAGEMENT. Asymptomatic patients with serum TSH levels between 4.5 and 10 μU per mL should have a repeat test every six to 12 months. Available data do not support a benefit for early treatment of subclinical hypothyroidism; therefore, the panel does not recommend treatment with levothyroxine for these patients.
What can cause subclinical hypothyroidism?
The causes of subclinical hypothyroidism are the same as those of (overt) hypothyroidism and include chronic lymphocytic (Hashimoto’s) thyroiditis, partial thyroidectomy, radioactive iodine therapy, and damage to the thyroid from radiation treatment.
Does subclinical hypothyroidism make you gain weight?
“Hypothyroidism from any cause results in a decrease in energy metabolism, or the basal metabolic rate. Patients often experience a modest amount of weight gain prior to diagnosis because of this metabolic slowing,” explains Northwestern Medicine Endocrinologist Eve D. Bloomgarden, MD.
Can you not treat subclinical hypothyroidism?
Adults with subclinical hypothyroidism should not be treated with thyroid hormones, according to a new guideline from The BMJ’s Rapid Recommendations panel.
Is subclinical hypothyroidism reversible?
Standard treatment for hypothyroidism involves taking a daily oral medication called levothyroxine, a synthetic form of thyroid hormone. It restores the body’s hormone levels to normal, which reverses the signs and symptoms of hypothyroidism.
Can you lose weight with subclinical hypothyroidism?
Frequently, patients with overt hypothyroidism complain of weight gain, and treatment of overt hypothyroidism may result in modest weight loss (2). However, the association between subclinical hypothyroidism and weight is less well characterized, especially in the elderly.