High levels of thyroid hormones, or hyperthyroidism, cause rapid bone loss, and new bone might not be as strong as the bone lost. This process of increased bone loss over time causes osteoporosis.
Can hyperthyroidism cause osteoporosis?
Overt hyperthyroidism is associated with accelerated bone remodeling, reduced bone density, osteoporosis, and an increase in fracture rate. The bone density changes may or may not be reversible with therapy.
Why does hyperthyroidism cause osteoporosis?
The thyroid releases 2 hormones: thyroxine (T4) and triiodothyronine (T3). If you have hyperthyroidism—that is, your body produces too much T4—you have an increased risk of developing osteoporosis because being hyperthyroid can trigger an imbalance of bone-eroding activity by the osteoclasts.
How does Graves disease affect the bones?
The increased level of thyroid hormones causes a reversible bone loss due to an expansion of the remodeling space and an irreversible loss due to a negative net bone balance and eventually an increased risk of trabecular perforations4. Thus, hyperthyroidism has been considered a major risk factor for osteoporosis1–4.
How does thyroid hormone affect bone?
Thyroid hormone (TH) plays an important role in normal endochondral ossification and is essential for skeletal development, linear growth, maintenance of bone mass, and efficient fracture healing (1).
Does thyroid affect bone density?
High levels of thyroid hormones, or hyperthyroidism, cause rapid bone loss, and new bone might not be as strong as the bone lost. This process of increased bone loss over time causes osteoporosis. Hypothyroidism, which slows your body’s metabolism, also slows down your bone’s metabolism.
Can I take calcium if I have hyperthyroidism?
Yes. Calcium supplements — or antacids containing calcium — can interfere with the absorption of thyroid hormone replacement medications, such as synthetic thyroid hormones levothyroxine (Synthroid, Unithroid, others) and liothyronine (Cytomel), as well as thyroid extract supplements.
Can an overactive thyroid cause bone pain?
It is frequently associated with bulging eyes and a rash on the legs, and often causes pain in the bones. Bursitis in hyperthyroidism. Bursitis, particularly of the shoulder joint, commonly occurs with an overactive thyroid gland. It may also occur surrounding other joint areas.
How does hyperthyroidism affect calcium levels?
Hyperthyroidism is associated with an increased excretion of calcium and phosphorous in the urine and stool, which results in a loss of bone mineral. This loss is documented by the measurement of bone density (densitometry) and leads to an increased risk of broken bones (fractures).
Does thyroid cause bone pain?
For some people, hypothyroidism can add to joint and muscle problems. Specifically, hypothyroidism may lead to: Muscle aches, tenderness and stiffness, especially in the shoulders and hips. Joint pain and stiffness.
Does vitamin D affect thyroid medication?
No interactions were found between levothyroxine and Vitamin D3. This does not necessarily mean no interactions exist. Always consult your healthcare provider.
Which mineral is associated with hyperthyroidism?
Hyperthyroidism caused a reduction in serum lipids, magnesium, and potassium. Thyroxine therapy normalized the deranged lipids and minerals, but not glucose. Results indicate that thyroid function tests should be considered when diagnosing those metabolic disorders.
What hormone is used to strengthen bones?
Three calcium-regulating hormones play an important role in producing healthy bone: 1) parathyroid hormone or PTH, which maintains the level of calcium and stimulates both resorption and formation of bone; 2) calcitriol, the hormone derived from vitamin D, which stimulates the intestines to absorb enough calcium and …
Does thyroid medicine affect your bones?
Too much thyroid medicine increases the activity of the osteoclasts (the bones that break down bone) and put you at an increased risk for breaking a bone.
Can thyroid problems affect calcium levels?
The thyroid gland governs metabolism, or how fast the cells in your body work. In rare cases of severe thyroid disease, blood calcium levels can become imbalanced.
How do thyroid hormones affect growth?
In addition to its complex metabolic effects involved in the general mechanisms of body growth, thyroid hormone stimulates the production of growth factors, particularly EGF and NGF. Moreover, it affects GH and somatomedin production and also their tissue activity.